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Nolvadex Nolvadex (tamoxifen) is supposed to be taken only by people diagnosed with breast cancer or those at risk of developing breast cancer. This medicine can be taken for up to 5 years (for breast cancer prevention), so it's important to plan your treatment ahead and discuss all the aspects of your treatment with your health care provider. You will need to know the most common side effects sometimes reported, such as hot flashes, headache, weight loss, dizziness, constipation, increased tumor pain, nausea, excessive tiredness, depression, thinning of hair, and stomach cramps. More serious side effects are also possible and can include loss of appetite, rash, blisters, restlessness, fever, vision problems, jaundice, unusual bruising or bleeding, and muscle weakness. Make sure you report the serious side effects right away to your doctor while the mild side effects mentioned are likely to go away on their own. However, if they do not go away and get more severe - you may want to talk to your health care provider about them. Take Nolvadex once or twice a day as recommended and make sure you never exceed the dose prescribed. Do not give Nolvadex to other people to whom it was not prescribed.

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